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  • Title: Effect of transdermally administered scopolamine on the vestibular system in humans.
    Author: Shojaku H, Watanabe Y, Ito M, Mizukoshi K, Yajima K, Sekiguchi C.
    Journal: Acta Otolaryngol Suppl; 1993; 504():41-5. PubMed ID: 8470531.
    Abstract:
    In order to elucidate the effect of scopolamine on the vestibular system in humans, various experimentally-induced forms of nystagmus, i.e. caloric nystagmus, rotational nystagmus, optokinetic nystagmus, visual-vestibular interaction and optokinetic after nystagmus, were evaluated before and after the administration of two pieces of Scopoderm-TTS or placebo patches retro-auricularly. Scopolamine reduced the responses of both the caloric and optokinetic after nystagmus compared with the placebo. The possible action site of this drug is discussed.
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