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  • Title: [An evaluation of the analgesic activity and tolerance of ST-679 in patients with pain following orthopedic and traumatological interventions].
    Author: De Santis E, La Pinta M, Nolfe G.
    Journal: Clin Ter; 1993 Jan; 142(1 Pt 2):53-9. PubMed ID: 8472522.
    Abstract:
    The analgesic efficacy and tolerability of ST-679 (administered in a single oral dose of 1200 mg) was evaluated in a double-blind parallel-group study, as compared with paracetamol (administered in a single oral dose of 1000 mg) on 40 patients with pain following orthopedic or traumatological surgery. ST-679 was shown to possess better analgesic qualities with respect to paracetamol, in that the effect establishes itself more quickly and, moreover, both the maximum analgesic activity performed as well as the constant level on which such activity tends to stabilize is greater. No adverse reaction was recorded for either treatment, but ST-679 demonstrated a better tolerability with regard to paracetamol.
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