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  • Title: A comparison of human immunodeficiency virus (HIV) seropositivity and hepatitis B surface antigenemia (HBs Ag) among the same group of apparently healthy pregnant women in Lagos, Nigeria: a preliminary report.
    Author: Obi CL, Anyiwo CE, Nnatu SN, Agbonlahor DE, Esumeh FI, Karpas A.
    Journal: Viral Immunol; 1993; 6(1):43-7. PubMed ID: 8476507.
    Abstract:
    Two hundred and fifty apparently healthy pregnant women attending the Obstetrics and Gynecology Clinic of the Lagos University Teaching Hospital (LUTH), Lagos, Nigeria were screened for a comparison of the prevalence of HIV seropositivity and hepatitis B surface antigenemia (HBs Ag) amongst them. The Karpas AIDS cell test for HIV seropositivity and Bioman Hepatitis test kits were used as described by the manufacturers. HIV seropositive cases were confirmed using the Western blot test. Results revealed that out of the 250 pregnant women screened, 2 (0.8%) and 11 (4.4%) were HIV-1 and HBs Ag seropositive, respectively. However, the same 2 pregnant women now constituting 2 (18.2%) of the 11 HBs Ag positive pregnant women were simultaneously HIV-1 seropositive. Antibody to HIV-2 was not recorded in all HIV seropositive cases. This is the first report on the simultaneous prevalence of HBs Ag and HIV seropositivity among apparently healthy pregnant women in Lagos, Nigeria. 250 sperm from apparently healthy pregnant patients at the Obstetrics and Gynecology Clinic at Lagos University Teaching Hospital, Lagos, Nigeria, were tested for HIV-1 and HIV-2 and hepatitis B surface antigen (HBsAg). Sera were screened for HIV with the Karpas AIDS cell test using HIV-1 and HIV-2 isolated in Great Britain, and confirmed with the Karpas confirming test and the Western blot. Bioman Hepatek kits were used for hepatitis screening. 2 pregnant women (0.8%) tested positive for HIV-1 and none for HIV-2. 11 women (4.4%) had HBsAg in their serum, and among these, 2 were positive for both HBsAg and HIV-1. This is the first report of pregnant women with both HIV and hepatitis virus screens in Lagos.
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