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  • Title: [Personal experience with the use of Rulid (roxithromycin) in children less than 1 year of age].
    Author: Jakubicka J, Dluholucký S.
    Journal: Cesk Pediatr; 1993 Jan; 48(1):49-51. PubMed ID: 8477469.
    Abstract:
    The authors give an account of the use of Roxithromycin (preparation Rulide) in children of the youngest age group, i.e. in infants. From January 1989 to April 1992 they treated 24 children under 5 weeks to 12 months of age with Roxithromycin. Roxithromycin was administered in amounts from 5 to 10 mg/kg after 12-hour intervals in the course of 4 to 12 days. In 22 children a favourable clinical effect was observed, in two children antibiotic treatment had to be changes because there was no clinical response. Undesirable effects, i.e. vomiting, during Roxithromycin were observed only in two children. In no instance was it necessary to discontinue treatment.
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