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  • Title: [Secondary arterial hypertension in type I neurofibromatosis (NF-1). Findings in 6 patients].
    Author: Vizcaíno I, Ferrer MD.
    Journal: Rev Clin Esp; 1993 Mar; 192(4):178-80. PubMed ID: 8480062.
    Abstract:
    With the aim to analyze the association of Type I Neurofibromatosis with secondary arterial hypertension, a retrospective study has been performed on 36 patients, diagnosed of pheochromocytoma (n = 12) and/or renal artery stenosis (n = 25), finding in 6 of them diagnostic criteria of Type I neurofibromatosis, of these 4 showed pheochromocytoma, 1 renal artery stenosis and 1 pheochromocytoma plus renal artery stenosis. CAT and angiography were the best diagnostic imaging methods to confirm clinic and biological suspicion of adrenal tumor of renal artery stenosis. It is recommended the systematized study of patients with NF-1 together with their relatives who phenotypically show some illness stigma, or with arterial hypertension resistant to conventional treatment.
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