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  • Title: Efficacy of the somatostatin analog octreotide in the treatment of two patients with refractory diabetic diarrhea.
    Author: Walker JJ, Kaplan DS.
    Journal: Am J Gastroenterol; 1993 May; 88(5):765-7. PubMed ID: 8480746.
    Abstract:
    Two patients with severe refractory diabetes-related diarrhea are described. One patient had steatorrhea. Both responded to octreotide during a mean follow-up period of 7 months. The pathophysiology of diabetic diarrhea and the potential mechanism of action of octreotide are discussed. The only adverse side effect reported was hypoglycemia in one of the patients, which required a reduction of the insulin dose. Octreotide is a safe and effective agent for the treatment of refractory diabetic diarrhea.
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