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Title: Childhood discoid lupus erythematosus. Author: George PM, Tunnessen WW. Journal: Arch Dermatol; 1993 May; 129(5):613-7. PubMed ID: 8481023. Abstract: BACKGROUND: Discoid lupus erythematosus (DLE) is uncommon in childhood. Less than 2% of patients with DLE develop the disease before 10 years of age. OBSERVATIONS: We present eight cases of childhood DLE with onset before age 10 years: four black boys with cutaneous DLE, three black girls ages 7, 2, and 6 years at onset, who developed systemic lupus erythematosus at ages 12, 9, and 8 years, respectively, and a 10-year-old Hispanic boy who had a systemic flare at the age of 20 years. CONCLUSIONS: A review of the 16 published cases of childhood DLE reveals that it is similar to its adult counterpart in its presentation and chronic course. However, several important differences are noted: a lack of female predominance, a low incidence of photosensitivity, and frequent progression to systemic lupus erythematosus at an early age. A discussion of the management of DLE in children is also presented.[Abstract] [Full Text] [Related] [New Search]