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  • Title: [Nevus spilus. A histopathological study (author's transl)].
    Author: Cramer HJ.
    Journal: Zentralbl Allg Pathol; 1977; 121(1-2):122-8. PubMed ID: 848167.
    Abstract:
    In the past, the nevus spilus was differently interpreted. Ito and Hamada, however, limited this term to a pigmented macule that had darker speckles within it. This newer definition is a useful one in clinical diagnostics. But histopathologically this lesion seems not to be an entity. A review of the literature and the present study suggest that it is in all probability a café-au-lait-nevus of neurofibromatosis-type. The darker spots are different in their histopathologic structures. They are nevus-cell-nevi, nevoid lentigines, epidermal pigmented macules or localized pigment disturbances with melaninincontinence following inflammatory prozesses.
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