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  • Title: [Lysosomes of blast cells in various cytochemical types of acute leukemia].
    Author: Mdzewski B, Lawkowicz W, Kolakowska-Polubiec K, Litwin J, Grabarczyk M, Rokicka R, Bielecka B.
    Journal: Acta Haematol Pol; 1977; 8(1):6-13. PubMed ID: 848251.
    Abstract:
    In 25 cases cytochemical types of acute leukemia were determined using the classification of Loeffler. Three cytochemical methods used were: p.a.S.-glycogen content, pox-peroxidase activity, and esterase activity determinatione. At the same time selective identification of lysosomes in perypheral blood blast cells was done using vital euchrisine staining and fluorescence microscopy. A correlation was observed between the cytochemical types of acute leukaemia and the lysosomal pattern. The fluorescence method of the identification of lysosomes is suggested for diagnosis of acute leukaemia.
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