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  • Title: d-alpha-Tocopherol inhibits low density lipoprotein induced proliferation and protein kinase C activity in vascular smooth muscle cells.
    Author: Ozer NK, Palozza P, Boscoboinik D, Azzi A.
    Journal: FEBS Lett; 1993 May 17; 322(3):307-10. PubMed ID: 8486164.
    Abstract:
    Native and malondialdehyde modified low density lipoproteins have been shown to stimulate smooth muscle cell proliferation (A7r5) in vitro. The stimulation is associated with an increase of protein kinase C activity. d-alpha-Tocopherol, at physiological concentrations, has been found to inhibit both protein kinase C activity and cell proliferation.
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