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Title: Localization of the gene-encoding upstream stimulatory factor (USF) to human chromosome 1q22-q23. Author: Shieh BH, Sparkes RS, Gaynor RB, Lusis AJ. Journal: Genomics; 1993 Apr; 16(1):266-8. PubMed ID: 8486371. Abstract: The upstream stimulatory factor, USF, is a ubiquitously expressed cellular transcription factor that binds to a symmetrical DNA sequence that is found in a variety of viral and cellular promoters. A full-length cDNA encoding the 43-kDa USF protein has previously been isolated. USF contains both helix-loop-helix and leucine repeats, which are involved in regulating its DNA binding and dimerization properties. We report the use of mouse-human somatic cell hybrids and in situ hybridization in localizing the gene-encoding USF to human chromosome 1q22-q23.[Abstract] [Full Text] [Related] [New Search]