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  • Title: Estimated median survival times of patients with colorectal cancer based on experience with 9,745 patients.
    Author: Silverman DT, Murray JL, Smart CR, Brown CC, Myers MH.
    Journal: Am J Surg; 1977 Mar; 133(3):289-97. PubMed ID: 848658.
    Abstract:
    From the End Results Group file at the National Cancer Institute, 9,745 colorectal cancer patients diagnosed from 1965 through 1971 and classified as adenocarcinoma NOS were selected to evaluate the joint effect of various prognostic factors on MST. A technic was developed which enables a physician to estimate the MST for a patient with a given set of patient/disease characteristics. The results are also summarized in an appendix, allowing the physician to bypass the calculation and refer directly to the MST. These results will aid the physician in determining whether a patient is at sufficiently high risk to warrant adjuvant therapy. The survival experience of this broad historical group of patients with varying prognostic factors can also serve as a basis for comparison of results of studies on highly selected patients treated in various experimental ways.
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