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  • Title: Absence of linkage between chromosome 21 loci and familial amyotrophic lateral sclerosis.
    Author: King A, Houlden H, Hardy J, Lane R, Chancellor A, de Belleroche J.
    Journal: J Med Genet; 1993 Apr; 30(4):318. PubMed ID: 8487280.
    Abstract:
    Familial amyotrophic lateral sclerosis (FALS) has recently been shown to be linked to chromosome 21 markers in a subset of families. However, we were unable to show linkage between FALS and chromosome 21 markers which flank the putative FALS locus in UK families.
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