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  • Title: [The role of eosinophil chemotactic factor in localized tissue eosinophilia by parasitic infection].
    Author: Ishimitsu T, Torisu M.
    Journal: Nihon Rinsho; 1993 Mar; 51(3):675-80. PubMed ID: 8492442.
    Abstract:
    Eosinophil chemotactic factors (ECFs) are thought to play an important role in the recruitment of eosinophils to parasitic inflammatory regions. ECF-A derived from mast cells, lymphokines from lymphocytes and ECFs from complements are well known as host-derived ECFs. On the other hand, ECF from parasites (ECF-P) and cytokines such as ESP (eosinophil stimulation promoter) and interleukin-5 are reported to be responsible for the eosinophil accumulation in parasitic inflammatory regions. In a series of our experiments using Anisakis larvae, we discovered a mechanism of eosinophil recruitment which could be accelerated by priming with ECF-P in parasite infected eosinophil phlegmon.
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