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  • Title: [Association of breast cancer and cancer of the uterus. 34 case reports].
    Author: Le Bouëdec G, Kauffmann P, Richard JF, Le Roux S, Dauplat J.
    Journal: Rev Fr Gynecol Obstet; 1993 Mar; 88(3):136-41. PubMed ID: 8493440.
    Abstract:
    A retrospective series of 34 cases of breast cancer combined with uterine cancer is reported. Cancers of the endometrium differed from cervical cancers by their number, 2.2 x more frequent (22 vs 10) and by the sequence of onset: they generally precede breast cancer, whereas they tend to follow cervical cancers. In contrast to the breast cancer/uterine cervical cancer association, which is considered to be fortuitous, the breast cancer/cancer of the uterine body association appears to be determined by a hormonal context. Through a review of the literature, a unifying endocrine theory is constructed, based on the role of hyperestrogenesis in mammary and endometrial carcinogenesis.
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