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  • Title: [Malignant melanoma of the choroid associated with neurofibromatosis].
    Author: Bacin F, Kemeny JL, D'Hermies F, Rozan R, Decroix P, Dalens H, Kalifa C.
    Journal: J Fr Ophtalmol; 1993; 16(3):184-90. PubMed ID: 8496569.
    Abstract:
    A sixteen-year-old white girl with peripheral neurofibromatosis (NF1), who had been treated for a glioma of the optic nerves and chiasma developed a choroidal mass in her only functional eye. After a transchoroïdal biopsy, the pathologic examination disclosed a choroïdal melanoma of epithelioid cell type, using morphological criteria as well as an immunohistochemical study. After treatment with a ruthenium plaque, the tumor completely regressed over 4 months. According to the data of the literature, neurofibromatosis seems to predispose to the development of uveal melanomas.
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