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  • Title: Efficacy of moxidectin against a strain of Haemonchus contortus resistant to ivermectin, a benzimidazole and a salicylanilide.
    Author: Oosthuizen WT, Erasmus JB.
    Journal: J S Afr Vet Assoc; 1993 Mar; 64(1):9-12. PubMed ID: 8496899.
    Abstract:
    The efficacy of moxidectin at 0.2 mg kg-1 live body mass against the multiple anthelmintic resistant White River Krtz strain of H. contortus was determined and compared to that of ivermectin, a benzimidazole, a salicylanilide and levamisole. Moxidectin and levamisole were effective against this strain of H. contortus and reduced the arithmetic mean burdens of this parasite in the sheep by 99.98% and 99.59%, respectively, while the efficacy of ivermectin, albendazole and closantel was only 29.1%, 33.75% and 78.3%, respectively.
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