These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Transient fall and subsequent return of high aldosterone secretion by adrenal adenoma during continued dexamethasone administration.
    Author: Ganguly A, Chavarri M, Luetscher JA, Dowdy J.
    Journal: J Clin Endocrinol Metab; 1977 Apr; 44(4):775-9. PubMed ID: 849988.
    Abstract:
    Plasma aldosterone concentration was consistently decreased by 50% or more in 6 patients with aldosterone-producing adenoma on the first day of dexamethasone administration, only to rise subsequently with continued use of dexamethasone while plasma cortisol concentration remained suppressed. The secondary rise in plasma aldosterone was not related to measured changes in known stimuli of aldosterone secretion. It is probable that the observations result from intrinsic alteration of aldosterone synthesis in the adenoma during prolonged ACTH suppression.
    [Abstract] [Full Text] [Related] [New Search]