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  • Title: Septo-optic dysplasia associated with polyendocrine dysfunction.
    Author: Shammas NW, Brown JD, Foreman BW, Marutani DR, Maddela D, Tonner D.
    Journal: J Med; 1993; 24(1):67-74. PubMed ID: 8501404.
    Abstract:
    Septo-optic dysplasia (SOD) is a rare congenital disease that has been described in association with hypothalamic dysfunction. A case of polyendocrine dysfunction is described in a 22 year-old white female with septo-optic dysplasia. Findings included atrophic optic nerves, a cavum septum pellucidum and a small pituitary gland detected by magnetic resonance imaging. The patient had central diabetes insipidus, Hashimoto's thyroiditis, and gestational diabetes mellitus. A review of the literature is presented. A careful and detailed endocrine evaluation is needed in patients with SOD.
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