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  • Title: Epidural compression of the spinal cord caused by vertebral osteoblastic metastasis of prostate carcinoma. A case report.
    Author: Yamashita K, Ueda T, Komatsubara Y, Usami M, Ishiguro S, Kadota T.
    Journal: Clin Orthop Relat Res; 1993 Jun; (291):138-41. PubMed ID: 8504592.
    Abstract:
    A 71-year-old man with prostate cancer developed epidural compression of the spinal cord caused by bony protuberances expanding from a vertebral osteoblastic metastasis. Pathologic examination of the metastatic lesion showed that both tumor and thickened vertebral trabeculae broke through the cortex and formed bony protuberances. The periosteal new bone appeared not to arise from a reactive periosteum but from the tumor breaking through the cortex. A biologic interaction between the tumor and the host may be responsible for the rare periosteal new bone formation.
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