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  • Title: [Radiation therapy in the prevention of periarticular, heterotopic ossification following implantation of a total hip endoprosthesis].
    Author: Goldmann AR, Seegenschmiedt M, Andreas P, Hohmann D, Sauer R, Beck H.
    Journal: Z Orthop Ihre Grenzgeb; 1993; 131(2):151-5. PubMed ID: 8506732.
    Abstract:
    From June 1988 to January 1991 the efficacy of a low-dose (5 x 2 Gy) versus a high-dose (10 x 2 Gy, resp. 5 x 3,5 Gy) prophylactic postoperative radiotherapy was assessed in a prospective randomized trial. 60 patients at the highest risk for formation of heterotopic ossification (HO) were included in this study, i.e. patients that presented already HO in the ipsi- or contralateral hip at the time of surgery. After both irradiation regimen the incidence and severity of HO was significantly less than without prophylaxis; there was no significant difference (regarding the severity of HO, the hip score (16) and the hip mobility) between the two regimen.
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