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  • Title: Autoimmune haemolytic anaemia with the unusual combination of both IgM and IgG autoantibodies.
    Author: Freedman J, Newlands M.
    Journal: Vox Sang; 1977; 32(2):61-8. PubMed ID: 851007.
    Abstract:
    Two patients with autoimmune haemolytic anaemia of no obvious aetiology are presented. Both cases had IgM autoantibodies which were cold agglutinins with anti-I specificity and were complement binding. Both cases also had IgG autoantibodies which were incomplete, of wide thermal range and also had anti-I specificity, but were not complement binding. The red cells of both patients were coated with C4/C3d and IgG.
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