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  • Title: Multisection proton MR spectroscopic imaging of the brain.
    Author: Duyn JH, Gillen J, Sobering G, van Zijl PC, Moonen CT.
    Journal: Radiology; 1993 Jul; 188(1):277-82. PubMed ID: 8511313.
    Abstract:
    The authors developed a hydrogen-1 proton magnetic resonance (MR) imaging method in which metabolic information is acquired by obtaining multiple sections through the brain. A spin-echo sequence is used for section selection, an octangular outer volume saturation pulse for lipid suppression, and a chemical-shift-selective saturation pulse for water suppression. High-quality maps of choline, creatine, and N-acetylaspartate were obtained in six studies performed in four volunteers. Water and lipid signal from the skull area was well suppressed by the pulse sequence used.
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