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  • Title: The 6-ketoprostaglandin F1alpha pathway in the lamb ductus arteriousus.
    Author: Pace-Asciak CR, Rangaraj G.
    Journal: Biochim Biophys Acta; 1977 Mar 25; 486(3):583-5. PubMed ID: 851548.
    Abstract:
    Homogenates of the lamb ductus arteriosus at term have the capacity to convert exogenous arachidonic acid into prostaglandins E2, F2alpha and 6-ketoprostaglandin F1alpha. No evidence was obtained for the formation of prostaglandin D2 and thromboxane B2. All products were quantitated by mass spectrometry. 6-Ketoprostaglandin F1alpha was the major compound, formed in amounts in excess of 10 fold over prostalgandins E2 and F2alpha.
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