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  • Title: [Physico-chemical properties of the DNP-systems of leukemia cells with different chromosome numbers].
    Author: Svirnovskiĭ AI, Nikolaĭchik VV, Levin VI.
    Journal: Biull Eksp Biol Med; 1977 Jan; 83(1):82-5. PubMed ID: 851610.
    Abstract:
    The binding between the components of the isolated DNP-complex proved to be more stable in leukemic cells in comparison with the normal lymphoid spleen cells. This conclusion was based on the investigation of the thermomechanical and disaggregation properties of the supramolecular DNP systems isolated from leukemic cells. The change in the isolated DNP-complex were independent of the subpopulation variants of the leukemic lymphatic cells and their chromosome set (diploid or hyperdiploid). The observed changes in the chromatin properties were more specific for leukemic cells than the changes in thechromosome number.
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