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  • Title: [Several kinetic features of membrane-dependent monoamine oxidase].
    Author: Vasil'evykh LG, Gorkin VZ, Kagan ZS.
    Journal: Biull Eksp Biol Med; 1977 Mar; 83(3):288-9. PubMed ID: 851631.
    Abstract:
    The v versus (S) plots for the initial rates of serotonin oxidation, catalyzed by monoamine oxidase in fragments of the rat liver or bovine brain mitochondrial membrane, had complicated non-hyperbolic shape, suggesting kinetic manifestation of cooperation in binding the substrate by the enzyme. A possibility of interactions of different monoamine oxidase types via the conformational alterations in the bio-membrane itself is considered.
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