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  • Title: Cisapride in chronic dyspepsia: results of a double-blind, placebo-controlled trial.
    Author: Chung JM.
    Journal: Scand J Gastroenterol Suppl; 1993; 195():11-4. PubMed ID: 8516653.
    Abstract:
    The efficacy and tolerability of cisapride in chronic dyspepsia was evaluated in a randomized, double-blind, placebo-controlled study. After 4 weeks' treatment with oral cisapride 10 mg three times daily (n = 14), bloating and epigastric discomfort were significantly reduced compared with placebo (n = 15; p < 0.05). Moreover, the global response to treatment was excellent or good in 71.4% of patients in the cisapride group versus 20.0% with placebo. No significant side effects were observed. It is concluded that cisapride is an effective and well-tolerated treatment for chronic dyspepsia.
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