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  • Title: Ginkgolide BN 52021 protects against hemorrhagic shock-induced renal injury in rats.
    Author: Kirejczyk JK, Chyczewski L, Debek W.
    Journal: Rocz Akad Med Bialymst; 1995; 40(1):65-76. PubMed ID: 8528996.
    Abstract:
    Degree of renal damage in experimental untreated and treated hemorrhagic shock was estimated in light microscopy. Histological preparations were scored with a semiquantitative scale concerning the changes which are typical for the acute renal failure. It was found that an early treatment with the PAF-receptor antagonist (ginkgolide BN 52021) considerably reduced morphological changes observed in rat kidney in hemorrhagic shock, comparing with untreated shock and in shock treated with a polyelectrolyte solution.
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