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  • Title: Acute renal failure after exercise in a child with renal hypouricemia.
    Author: Fujieda M, Yokoyama W, Oishi N, Okada T, Kurashige T, Hamada G.
    Journal: Acta Paediatr Jpn; 1995 Oct; 37(5):642-4. PubMed ID: 8533596.
    Abstract:
    We describe a 15 year old boy with renal hypouricemia who developed acute renal failure after a school athletics meeting, accompanied by appendicitis. During acute renal failure, the highest level of uric acid was 5.0 mg/dL, creatinine 7.9 mg/dL and urea nitrogen 58.6 mg/dL. After recovery, the serum uric acid fell to 0.9 mg/dL and the fractional excretion of uric acid (FEuA) exceeded the normal range. The probenecid and pyrazinamide tests showed that the patient had a total defect of uric acid reabsorption. This case suggested that strenuous exercise could be responsible for acute renal failure in patients with renal hypouricemia.
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