These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Color-fluorescein relationship in glaucomatous optic nerve damage.
    Author: Tanaka Y.
    Journal: Jpn J Ophthalmol; 1995; 39(2):180-6. PubMed ID: 8538076.
    Abstract:
    With the assistance of a computerized image analysis system, the author obtained a quantitative evaluation of the color of the optic disc (%R) and the fluorescein intensity (%F) in glaucomatous eyes. Patients in various stages of glaucoma were studied, including 23 patients with primary open-angle glaucoma (POAG) (23 eyes), 22 patients with normal-tension glaucoma (NTG) (22 eyes), along with 11 normal controls (11 eyes). In both the POAG and NTG groups, %R was lower in eyes with more marked visual field defects. The correlation coefficient between %R and the stage of visual field defect was 0.794 (P < 0.001) in the POAG group and 0.652 (P < 0.001) in the NTG group. Fluorescein intensity also was lower in eyes with more marked visual field defects in both groups. The correlation coefficient between %F and the stage of visual field defect was 0.897 (P < 0.001) in the POAG group and 0.681 (P < 0.001) in the NTG group. In early-stage patients in both glaucoma groups, %R was significantly lower than that in the control group (P < 0.05). However, there was no significant difference in %R between the NTG and POAG groups. In these patients, %F was also lower than that in the control group (P = 0.001), and was significantly lower in the NTG group than in the POAG group (P = 0.01). In addition, the pattern of correlation differed between the two groups. This difference in the pattern of the optic disk color-fluorescein correlation suggests that pathological backgrounds in the development of glaucomatous optic disc damage are also different between POAG and NTG.
    [Abstract] [Full Text] [Related] [New Search]