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  • Title: [A case of failure of mitroflow pericardial valve with severe hemolytic anemia].
    Author: Ohkado A, Akiyama K, Hirota J, Shiina Y.
    Journal: Kyobu Geka; 1995 Nov; 48(12):1013-5. PubMed ID: 8538101.
    Abstract:
    A 49-year-old woman who underwent mitral valve replacement with 29 mm Mitroflow pericardial valve in 1985 started to have severe hematuria, anemia and icterus around May 1994. She was diagnosed to have mitral regurgitation with hemolytic anemia due to structural deterioration of the prosthetic valve. She underwent replacement of the prosthetic valve with 29 mm St. Jude medical mechanical valve, which alleviated the symptoms remarkably. The explanted valve showed an extensive cuspal tear and prolapse close to the commissure and poor endothelialization of the inflow surface of the frame. In our experience the rate of structural deterioration of the Mitroflow valve is so high that we discontinued using this bioprosthesis.
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