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Title: Syndrome of inappropriate antidiuretic hormone secretion in papillary serous surface carcinoma of the peritoneum. Author: Resnik E, Bender D. Journal: J Surg Oncol; 1996 Jan; 61(1):63-5. PubMed ID: 8544463. Abstract: A case of syndrome of inappropriate antidiuretic hormone secretion (SIADH) in a patient with suboptimally cytoreduced stage III papillary serous surface carcinoma of the peritoneum is described. After the primary surgery, the patient refused further therapy. Within a month bilateral pleural effusions and abdominal ascites compelled the patient to accept treatment with carboplatin and cyclophosphamide. Ten days following the chemotherapy, she was admitted in a disoriented state with serum sodium of 117-mEq/L. During the evaluation, treatment, and subsequent follow-up, the diagnosis of SIADH was confirmed. Numerous disease processes have been associated with the development of SIADH; however, there have been few reports in gynecologic malignancies. Possible etiology and clinical management of this patient are briefly discussed.[Abstract] [Full Text] [Related] [New Search]