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PUBMED FOR HANDHELDS

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  • Title: Molecular genetics of androgenic 17 beta-hydroxysteroid dehydrogenases.
    Author: Andersson S.
    Journal: J Steroid Biochem Mol Biol; 1995 Dec; 55(5-6):533-4. PubMed ID: 8547178.
    Abstract:
    17 beta-Hydroxysteroid dehydrogenase (17 beta-HSD) type 2 catalyzes the NAD(+)-dependent oxidation of androgens, estrogens and progestins, predominantly in the secretory endometrium, placenta, liver and small intestine. 17 beta-HSD type 3 catalyzes the NADPH-dependent conversion of androstenedione to testosterone in the testis, and the genetic disease 17 beta-HSD deficiency is caused by mutations in the 17 beta-HSD3 gene.
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