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  • Title: The effect of hyperbaric oxygen on different phases of healing of ischaemic flap wounds and incisional wounds in skin.
    Author: Quirinia A, Viidik A.
    Journal: Br J Plast Surg; 1995 Dec; 48(8):583-9. PubMed ID: 8548161.
    Abstract:
    Several studies have revealed a positive effect of treatment of ischaemic wounds and flaps with hyperbaric oxygen. We studied the effect of 100% oxygen (2.4 ATA) for 90 min daily on different phases of healing ischaemic and normal incisional wounds in rats. Hyperbaric oxygen on day 0-3 significantly increased almost all the force parameters of ischaemic flap wounds by 41-57% after 10 days of healing. On the other hand, when the treatment was continued until day 9 the positive effect on the wound healing was abolished. Furthermore, when hyperbaric oxygen was given on days 4-9 there was a tendency towards a decrease in the biomechanical parameters. Hyperbaric oxygen had no effect on the healing of normal incisional wounds.
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