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  • Title: [Flubiprofen vs dipyrone combined with hyoscine: the analgesic efficacy in renal colic].
    Author: Mora Durban MJ, Extramiana Cameno J, Arrizabalaga Moreno M, Paniagua Andrés P, Camp Herrero J, Milla Santos J, del Nogal Saez F, Gimeno Albo F, Moreno Carretero E, Domínguez Granados R.
    Journal: Arch Esp Urol; 1995 Nov; 48(9):867-73. PubMed ID: 8554391.
    Abstract:
    OBJECTIVE: We compared the efficacy of flurbiprofen (NSAID) versus dipirone + hyoscine N-butylbromide in the treatment of nephric colic. METHODS: The study comprised 135 patients, aged 18 to 75 yrs, with intense nephric colic. The patients were observed 60 min after a single IM dose of 150 mg flurbiprofen (n = 67) or 2 gm dipirone + 20 mg hyoscine N-butylbromide. RESULTS: Both treatment modalities were well-tolerated and afforded significant pain relief. Flurbiprofen, however, was faster-acting and superior to dipirone + hyoscine in the overall evaluation of good and excellent therapeutic response rates. CONCLUSION: The results of the study show that IM flurbiprofen is a useful alternative to dipirone + hyoscine N-butylbromide in the treatment of nephric colic.
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