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  • Title: [Pulmonary metastases of glioblastoma].
    Author: Granjon O, Lange F, Authier FJ, Lebargy F.
    Journal: Rev Mal Respir; 1995; 12(5):489-91. PubMed ID: 8560081.
    Abstract:
    Extracranial metastases arising from primary brain tumors are very unusual. We report a case of glioblastoma with intra-thoracic spread characterized by mediastinal lymph nodes metastasis and bronchial, lung parenchyma and pleura carcinomatous lymphangitis. Pathologic findings are consistent with non-differentiated cell proliferation but Glial Fibrillary Acidic Protein immunodetection can be helpful to relate such a non-differentiated cell proliferation to its glial origin. The mechanisms of extra-cerebral spread are discussed according to autopsic findings and to the data reported in the literature.
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