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  • Title: [The correlation of dopamin- and enkephalinergic influences on rat conditioned-reflex activity].
    Author: Shugalev NP, Hartman G.
    Journal: Zh Vyssh Nerv Deiat Im I P Pavlova; 1995; 45(5):909-13. PubMed ID: 8560937.
    Abstract:
    Behavioural effects of enkephalin microinjections into substantia nigra of rat brain were studied in short time after intrastriatal administration of 6-hydroxydopamine (6-OHDA). It was shown that such microinjections improved conditioned activity of animals. A conclusion was made that the role of enkephalinergic brain structures in compensatory processes in acute period of development of 6-OHDA neurotoxic action was related to increase in efficiency of the mechanisms of self-regulation of dopamine neurons.
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