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  • Title: [Changes in myocardial ATPase activity and Ca2+ content in burned rats].
    Author: Huan J, Chen Y, Ge S.
    Journal: Zhonghua Wai Ke Za Zhi; 1995 Jul; 33(7):400-2. PubMed ID: 8565726.
    Abstract:
    The myocardial ATPase activity and Ca2+ content were investigated in rats with full thickness skin burn injury of 30% TBSA. The results showed that there were significant inhibitions of Na+, K(+)-ATPase,Ca2+, Mg(2+)-ATPase, and Ca(2+)-ATPase activities of myocardium after burn injury. The burn injury could result in increase of calcium content in myocardium. Burned rats also had a higher level of MDA in heart tissue when compared to controls. This study demonstrates that the membrane defects with respect to ATPase activity, oxygen free radical, and Ca2+ overload in myocardium may be associated with damage of myocardium after burns.
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