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  • Title: Experimental infection with Ancylostoma caninum larvae in mice. V. Serum protein pattern during infection with various doses.
    Author: Bhopale MK, Johri GN.
    Journal: J Hyg Epidemiol Microbiol Immunol; 1978; 22(3):319-27. PubMed ID: 85675.
    Abstract:
    Serum protein patterns of Swiss albino mice during Ancylostoma caninum infection with varying dose levels were studied electrophoretically. There was a significant decrease in albumin associated with a corresponding increase in beta globulin in all the infected groups. Gamma globulin decreased significantly in all groups except the one infected with a challenge dose of 4000 larvae. Maximum changes occurred on day 31, 15, 9, 15 and 6 when mice were infected with 250, 500, 1000, 2000 and 4000 larvae, respectively. There was a significant negative correlation between albumin and the infective doses and a positive correlation between beta globulin and the infective doses and among the changes caused by different infective doses.
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