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  • Title: On the nature of the link between malignant hyperthermia and exertional heatstroke.
    Author: Bourdon L, Canini F.
    Journal: Med Hypotheses; 1995 Sep; 45(3):268-70. PubMed ID: 8569550.
    Abstract:
    Malignant hyperthermia (MH) is a rare myopathy inducing severe accident when carriers are exposed to triggering agents. MH susceptibility (MHS) is assessed by pharmacological tests performed on muscle strips. Exertional heat stroke (EHS) is a severe accident occurring during long and strenuous exercise. It has been observed that numerous EHS patients are susceptible to MH according to pharmacological tests. Because most of those EHS-MHS subjects were soldiers, we hypothesize that military duty could select subjects with infraclinical myopathy and therefore would increase the MHS:EHS subject ratio.
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