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  • Title: [The interferon status and cellular immunity of pregnant women with viral hepatitis B].
    Author: Akhmedova MD, Zmyzgova AV, Karimova MT.
    Journal: Ter Arkh; 1995; 67(11):7-10. PubMed ID: 8571261.
    Abstract:
    The examination of 62 pregnant women with acute viral hepatitis B has established in them inhibition of interferon genesis and the presence of secondary T-cell immunodeficiency. The most pronounced and long-lasting was a fall of gamma-interferon. A simultaneous lowering of alpha-, gamma- and serum interferon was indicative of complicated pregnancy or premorbid condition. A persistent deficient production of gamma-interferon and T lymphocytes, imbalance of their subpopulations promoted long-term course of hepatitis and persistence of HBsAg.
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