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  • Title: [Diagnostic efficiency of histological and simple microbiological tests for Helicobacter pylori detection in a community hospital].
    Author: Mitry E, Leneveu M, Vitte RL, Wesenfelder L, Felsenheld C, Eugene C, Bergue A.
    Journal: Ann Gastroenterol Hepatol (Paris); 1995 Oct; 31(5):281-3. PubMed ID: 8572562.
    Abstract:
    The objective of this study was to compare histology and microbiology (direct method, urease test, culture) for the detection of Helicobacter pylori in antral biopsies. Thirty-six patients, aged between 18 and 82, with a peptic ulcer (active or not), or gastritis or duodenitis were studied. Eighteen patients (50%) had a positive culture, 17 (47%) had a positive urease test, 16 (41%) had positive direct microbiology and 15 (42%) had positive histology. Correlation between histology and culture was 84%. This study confirms the good sensitivity of histology and the urease test for the detection of Helicobacter pylori. Combination of both methods could optimise detection of the organism.
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