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  • Title: Mitochondrial nitric oxide synthase: a ubiquitous regulator of oxidative phosphorylation?
    Author: Bates TE, Loesch A, Burnstock G, Clark JB.
    Journal: Biochem Biophys Res Commun; 1996 Jan 05; 218(1):40-4. PubMed ID: 8573169.
    Abstract:
    In this article we demonstrate the immunocytochemical localization of nitric oxide synthase in mitochondria isolated from heart, skeletal muscle, and kidney, using a monoclonal antibody directed against the endothelial form of nitric oxide synthase. The possibility that mitochondrially located nitric oxide synthase is a ubiquitous regulator of mitochondrial oxidative phosphorylation in mammalian cells is discussed.
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