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  • Title: Serological and microbiological findings on 3 farms with equine leptospiral abortions.
    Author: Williams DM, Smith BJ, Donahue JM, Poonacha KB.
    Journal: Equine Vet J; 1994 Mar; 26(2):105-8. PubMed ID: 8575369.
    Abstract:
    Blood and urine samples from horses on 3 central Kentucky horse farms with prior histories of leptospiral abortions were analysed. Blood samples were obtained from all available horses on each farm and tested for antibodies to 6 leptospira serovars. Urine samples were collected from non-gravid mares with serum antibody titres > or = 1:800 and examined for leptospires by dark-field microscopy, fluorescent antibody testing and culture. Adult horses had the greatest serological evidence of exposure to leptospira, followed by yearlings, then foals. Of horses with anti-leptospiral antibodies, 76.3% reacted against serovar bratislava, 49.1% against icterohaemorrhagiae, 20.1% against grippotyphosa, 16.3% against pomona genotype kennewicki, 15.9% against hardjo and 1.0% against canicola. These findings confirmed that horses in central Kentucky are exposed to multiple leptospira serovars. The seroprevalence of antibodies to the 6 selected serovars was consistent among the 3 selected farms. There was no direct correlation between the serovar that was the cause of abortion in the previous season and prevalence of positive titres to that serovar in horses tested on the farms in the following year. Furthermore, there was no evidence of long-term urinary shedding of leptospira by horses with high leptospira antibody titres.
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