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  • Title: Bone changes in postmenopausal Thai women with or without hormonal replacement therapy.
    Author: Limpaphayom K, Taechakraichana N, Poshyachinda M, Jaisamrarn U.
    Journal: J Med Assoc Thai; 1995 Nov; 78(11):573-7. PubMed ID: 8576666.
    Abstract:
    UNLABELLED: Bone mass measurement was performed in 95 healthy postmenopausal women to assess the effect of hormonal replacement therapy (HRT) on bone changes. Women in the study group (51/95) received estrogen with or without progestin. The control group (44/95) did not receive any hormone regimen. The measurement was done at lumbar spines (L1-L4) and hip by dual energy X-ray absorptiometer at 0, 6 and 12 months. The results revealed significantly higher per cent changes of bone density of lumbar spines and hip, at 12 months, in the study group than in the control. ( STUDY: Lumbar Spine +1.76%, Hip +3.57%; CONTROL: Lumbar spines -2.32%, Hip +1.32%, P < 0.05). In conclusion, this study showed the value of hormonal replacement therapy for prevention of postmenopausal bone loss in Thai women.
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