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  • Title: Isoforms of glucose transporter in the iris-ciliary body.
    Author: Tsukamoto H, Mishima HK, Kurokawa T, Kiuchi Y, Sato E, Ishibashi S.
    Journal: Jpn J Ophthalmol; 1995; 39(3):242-7. PubMed ID: 8577074.
    Abstract:
    Isoforms of the facilitated glucose transporter (GLUT) were identified in the iris-ciliary body. Western blot analysis showed that GLUT1 and GLUT4 proteins were expressed in the rat iris-ciliary body. In addition, the content of GLUT proteins in the rabbit iris-ciliary body was estimated by specific [3H]cytochalasin B binding assay. The content of GLUT proteins was found to be more abundant in the iris-ciliary body than in the cerebral cortex. The utilization of glucose in the iris-ciliary body and the transport of glucose into the aqueous humor are suggested to be mediated by GLUT1 and GLUT4 proteins.
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