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  • Title: The effect of altering thyroid hormone concentrations on plasma gonadotrophins in postmenopausal women.
    Author: Taylor MA, Chapman C, Hayter CJ.
    Journal: Br J Obstet Gynaecol; 1977 Apr; 84(4):254-7. PubMed ID: 857863.
    Abstract:
    Plasma gonadotrophin levels were measured at frequent intervals in six postmenopausal thyrotoxic women treated with carbimazole. All patients showed an increasing follicle stimulating hormone/luteinizing hormone (FSH/LH) ratio as the thyroid hormone concentrations fell to normal and then into the hypothyroid range. Although the increased FSH/LH ratio was primarily due to a rise of FSH, two patients had a rise of both gonadotrophins. It is suggested that menstrual irregularities occurring in premenopausal women with disorders of thyroid metabolism may be related to similar changes.
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