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  • Title: [Pathomorphology of kidney lesions induced by non-steroidal anti-inflammatory drugs].
    Author: Postishil' IuA.
    Journal: Arkh Patol; 1995; 57(5):70-4. PubMed ID: 8579501.
    Abstract:
    Pathomorphological findings on nephrobiopsies from two groups of patients with NSAID-induced kidney lesions are provided. In the first group (9 patients) the disease developed in patients of different age after short-term use of NSAID and was clinically manifested by acute renal failure with extrarenal allergic symptoms (skin, rash, eosinophilia). Morphological features were acute tubulo-interstitial nephritis without glomerular lesions. In the second group (23 patients) the disease developed after longterm use of NSAID in older patients with a compromised renal blood circulation presenting clinically with nephrotic syndrome, and morphologically by acute tubulo-interstitial nephritis with minimal change (lipoid nephrosis).
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