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  • Title: [Observation on the animal model of hypoxic-ischemic encephalopathy and the change of pathology in newborn pigs].
    Author: Li W, Yao Y, Tan J.
    Journal: Hua Xi Yi Ke Da Xue Xue Bao; 1995 Sep; 26(3):330-3. PubMed ID: 8586404.
    Abstract:
    Thirty newborn pigs within 3 days of life were randomly divided into different groups according to the time of hypoxic-ischemic encephalopathy. The results showed that the brain damage and pathologic changes were most obvious in the 60 min hypoxia-ischemic group. Brain edema was observed in every group, especially in the group where hypoxia-ischemic lasted for more than 30 min. Cerebromalacia and hemorrhage in ventricles of brain and in arachnoid were observed, and these were particularly noticed in the group where hypoxia-ischemia lasted for 60 min.
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