These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: [The use of measuring serum soluble IL-2 receptor levels in cyclosporine-A treated lupus nephritis].
    Author: Zheng X, Lin M, Cui X, Yao Q, Zhou G, Guo Z.
    Journal: Hua Xi Yi Ke Da Xue Xue Bao; 1995 Sep; 26(3):338-41. PubMed ID: 8586406.
    Abstract:
    Twenty-one patients with Lupus Nephritis (LN) were treated with cyclosporine-A (CsA) for three months. Serum soluble interleukin-2 receptors (SIL-2R) were measured before and after treatment and correlated prospectively with serologic findings of LN activity. The patients had significantly higher IL-2R level before treatment (during LN flare) than after treatment (disease remission). A significant positive correlation was present between serum SIL-2R and proteinuria, and ANA as well, whereas the SIL-2R levels in LN patients were inversely correlated with serum levels of C3 and CH50. These observations suggest that serum SIL-2R level is an useful marker of disease activity in LN and may serve as a helpful adjunct in the management of this disorder.
    [Abstract] [Full Text] [Related] [New Search]